| Fecha | Hora | Casa | Fuera | Fase | TV | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
D | 2021-07-18 | 19:00 | Santos Laguna |  | 1-2 |  | América | 1F | ||||
V | 2021-07-24 | 03:00 | Mazatlán |  | 0-2 | | Santos Laguna | 1F | ||||
E | 2021-08-03 | 04:00 | Santos Laguna | | 0-0 |  | Club Tijuana | 1F | ||||
V | 2021-08-10 | 00:00 | Necaxa |  | 0-3 | | Santos Laguna | 1F | ||||
E | 2021-08-17 | 04:00 | Santos Laguna | | 2-2 |  | Atlas | 1F | ||||
V | 2021-08-24 | 02:00 | Club León |  | 1-6 | | Santos Laguna | 1F | ||||
V | 2021-08-31 | 04:00 | Santos Laguna | | 4-0 |  | Cruz Azul | 1F | ||||
V | 2021-09-05 | 19:00 | Puebla |  | 2-3 | | Santos Laguna | 1F | ||||
V | 2021-09-13 | 04:00 | Santos Laguna | | 5-4 |  | Chivas | 1F | ||||
E | 2021-09-28 | 00:00 | Santos Laguna | | 2-2 |  | Monterrey | 1F | ||||
V | 2021-10-05 | 04:00 | Juárez |  | 1-2 | | Santos Laguna | 1F | ||||
D | 2021-10-09 | 23:00 | Toluca |  | 1-0 | | Santos Laguna | 1F | ||||
V | 2021-10-19 | 00:00 | Santos Laguna | | 2-0 |  | Pumas | 1F | ||||
V | 2021-11-02 | 04:00 | Santos Laguna | | 3-1 |  | Atlético San Luis | 1F | ||||
D | 2021-11-09 | 02:00 | Pachuca |  | 4-0 | | Santos Laguna | 1F | ||||
D | 2021-11-14 | 00:00 | Querétaro |  | 4-2 | | Santos Laguna | 1F | ||||
D | 2021-11-22 | 04:00 | Santos Laguna | | 0-2 |  | Tigres | 1F | ||||
